Fig. 1 · Structure
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Glucocerebrosidase-IN-1 hydrochloride
Cat. No.
A75088
CAS
2279945-77-4
Glucosidase Inhibitor
Glucocerebrosidase-IN-1 hydrochloride is a potent and selective inhibitor of glucocerebrosidase (GCase), demonstrating an IC50 of 29.3 μM and a Ki of 18.5 μM. This compound is relevant for research applications concerning Gaucher disease and Parkinson's disease, as it influences cellular metabolism of glucocerebrosides. Its selective inhibition makes it a valuable tool for studying the biochemical pathways associated with these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2279945-77-4 |
| Applications | Glucosidase Inhibitor |
| Formula | C13H28ClNO3 |
| Molecular Weight | 281.82 |
| SMILES | O[C@@H]1[C@@H](CCCCCCCC)NC[C@@H](O)[C@H]1O.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.