Glucocorticoid receptor-IN-1 is a selective modulator of the glucocorticoid receptor (GR) known for its potent anti-inflammatory properties. It demonstrates significant transcriptional repressive activity with an IC50 of 2.11 nM against human matrix metalloproteinase 1 (hMMP1) and exhibits transcriptional activation with an EC50 of 5.59 nM against mouse mammary tumor virus (MMTV). This compound is suitable for research applications focused on inflammation and GR signaling pathways.
Glucocorticoid receptor-IN-1 is a selective modulator of the glucocorticoid receptor (GR) known for its potent anti-inflammatory properties. It demonstrates significant transcriptional repressive activity with an IC50 of 2.11 nM against human matrix metalloproteinase 1 (hMMP1) and exhibits transcriptional activation with an EC50 of 5.59 nM against mouse mammary tumor virus (MMTV). This compound is suitable for research applications focused on inflammation and GR signaling pathways.
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