Fig. 1 · Structure
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Glucosylceramide (gaucher's spleen)
Sphingolipid
Glucosylceramide is a sphingolipid that plays a significant role in cellular signaling and membrane structure. This compound is found in both neuronal and non-neuronal mammalian tissues, as well as in trace amounts in various plant species. Elevated levels of glucosylceramides contribute to cellular protection and facilitate cell proliferation, but they are also associated with obesity-related insulin resistance in murine models and neurodegenerative deficits specific to neuronopathic Gaucher disease. This reagent can be utilized in studies exploring lipid metabolism, cellular signaling pathways, and the pathophysiology of related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 85305-87-9 |
| Applications | Sphingolipid |
| Formula | C48H93NO8 (for lignoceryl) |
| Molecular Weight | 812.3 |
| Synonyms | Glucocerebrosides; Gaucher cerebroside; GluCers (gaucher's spleen) |
| SMILES | O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O)OC[C@H](NC([R])=O)[C@@H](/C=C/CCCCCCCCCCCCC)O)CO)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.