Fig. 1 · Structure
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Glutaminase C-IN-2
Glutaminase Inhibitor
Glutaminase C-IN-2 is an allosteric inhibitor of glutaminase C (GAC), exhibiting an IC50 value of 10.64 nM. This compound modulates cellular metabolism by inhibiting glutamine utilization, leading to elevated levels of reactive oxygen species (ROS). Glutaminase C-IN-2 demonstrates potential anticancer activity, making it a valuable tool for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3056437-77-2 |
| Applications | Glutaminase Inhibitor |
| Formula | C24H23N7O2S |
| Molecular Weight | 473.55 |
| SMILES | O=C(NC1=NN=C(N[C@H]2CN(C3=NN=CC=C3)CC2)S1)CC4=CC=CC(OC5=CC=CC=C5)=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.