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Glutaminase C-IN-3

GAC Allosteric Inhibitor

Glutaminase C-IN-3 is a potent allosteric inhibitor of Glutaminase C (GAC) with an EC50 of 116 nM. This compound modulates cellular metabolites and enhances reactive oxygen species (ROS) production by inhibiting glutamine metabolism. Glutaminase C-IN-3 demonstrates significant antitumor activity in A549 xenograft mouse models, making it a valuable tool for research in non-small cell lung cancer (NSCLC).

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3120156-36-4
Applications	GAC Allosteric Inhibitor
Formula	C₃₁H₃₁F₃N₆O₅S
Molecular Weight	656.68
SMILES	O=C(OC(C)C)C1=CC=CC(CC(NC2=NN=C(CCCCC3=NN=C(NC(CC4=CC=CC(OC(F)(F)F)=C4)=O)C=C3)S2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.