Gly-Gly-Gly-PEG4-azide is an ADC linker primarily used in the synthesis of antibody-drug conjugates (ADCs). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with bicyclo[6.1.0]nonyne (DBCO) or bicyclo[4.1.0]heptene (BCN) moieties, making it a versatile tool in chemical biology research and drug development applications.
Gly-Gly-Gly-PEG4-azide is an ADC linker primarily used in the synthesis of antibody-drug conjugates (ADCs). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with bicyclo[6.1.0]nonyne (DBCO) or bicyclo[4.1.0]heptene (BCN) moieties, making it a versatile tool in chemical biology research and drug development applications.
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