GNE-049

Catalog No.: A20206

CBP inhibitor

GNE-049

GNE-049 Chemical Structure

CAS NO. 1936421-41-8

GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$480.00
10 mg
$800.00
50 mg
$2,500.00
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Biological Activity

GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.93 mL 195.86 mL
0.5 mM 3.92 mL 19.59 mL 39.17 mL
1 mM 1.96 mL 9.79 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20206
Actions Inhibitor
M. Wt 510.58
Formula C27H32F2N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1936421-41-8
Synonyms GNE049, GNE 049
SMILES CC(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)=O

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