Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

GNE-049

Catalog No.: A20206

CBP inhibitor

GNE-049

GNE-049 Chemical Structure

CAS NO. 1936421-41-8

GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$480.00
10 mg
$800.00
50 mg
$2,500.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.93 mL 195.86 mL
0.5 mM 3.92 mL 19.59 mL 39.17 mL
1 mM 1.96 mL 9.79 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20206
Actions Inhibitor
CAS No. 1936421-41-8
Formula C27H32F2N6O2
M. Wt 510.58
Purity >98%
Synonyms GNE049, GNE 049
SMILES CC(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy GNE-049 | GNE-049 Supplier | purchase | cost | manufacturer | order | distributor | buy 1936421-41-8| 1936421-41-8 Supplier | purchase 1936421-41-8 | 1936421-41-8 cost | 1936421-41-8 manufacturer | order 1936421-41-8 | 1936421-41-8 distributor
Rewards