GNE 0723

Catalog No.: A12757

NMDAR modulator

GNE 0723

GNE 0723 Chemical Structure

CAS NO. 1883518-31-7

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.38 mL 106.89 mL 213.78 mL
0.5 mM 4.28 mL 21.38 mL 42.76 mL
1 mM 2.14 mL 10.69 mL 21.38 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12757
Actions Modulator
M. Wt 467.78
Formula C16H8ClF6N5OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1883518-31-7
Synonyms GNE0723, GNE-0723
SMILES N#C[[email protected]]1[[email protected]](C2=C(C(F)(F)F)SC3=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC(N32)=O)C1

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