GNE-495

Catalog No.: A12230

MAP4K4 inhibitor

GNE-495

GNE-495 Chemical Structure

CAS NO. 1449277-10-4

GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$155.00
50 mg
$460.00
100 mg
$920.00
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Biological Activity

GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.67 mL 123.33 mL 246.66 mL
0.5 mM 4.93 mL 24.67 mL 49.33 mL
1 mM 2.47 mL 12.33 mL 24.67 mL
5 mM 0.49 mL 2.47 mL 4.93 mL

*The above data is based on the productmolecular weight 405.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12230
Actions Inhibitor
CAS No. 1449277-10-4
Formula C22H20FN5O2
M. Wt 405.42
Solubility DMSO
Purity >98%
Synonyms GNE495, GNE495
SMILES O=C(C1=C2C=CC(C3=CC=CC(F)=C3)=NC2=C(N)N=C1)NC4CN(C(C5CC5)=O)C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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