GNE 5729

Name: GNE 5729
Brand: Adooq Bioscience
SKU: A20295
Rating: 5 (288 reviews)

Catalog No.: A20295

NMDAR modulator

GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$775.00	In stock
10mg	$1,245.00	In stock
25mg	$1,515.00	In stock
50mg	$1,975.00	In stock
100mg	$2,495.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description

GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A20295
Formula	C17H10Cl2F3N5O
Molecular Weight	428.2
CAS Number	2026635-66-3
SMILES	ClC1=C([C@H]2[C@H](C#N)C2)N3C(C=C1)=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC3=O
Synonyms	GNE-5729; GNE5729
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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