Fig. 1 · Structure
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Gossypolone
Musashi-1 Inhibitor
Gossypolone is a potent inhibitor of the RNA-binding protein Musashi-1, with a Ki value of 12 nM. It disrupts the interaction between Musashi and numb RNA by binding directly to the RNA-binding domain 1 (RBD1) of the MSI1 protein. This compound is valuable for cancer research, particularly in studies focusing on the regulatory roles of Musashi-1 in cancer cell biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4547-72-2 |
| Applications | Musashi-1 Inhibitor |
| Formula | C30H26O10 |
| Molecular Weight | 546.52 |
| SMILES | O=CC1=C(C(O)=C(C2=C1C(C(C(C3=O)=C(C(C4=C3C(C=O)=C(C(O)=C4C(C)C)O)=O)C)=C(C2=O)C)=O)C(C)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.