Fig. 1 · Structure
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GP130-IN-1
GP130 Inhibitor
GP130-IN-1 is a selective inhibitor of the GP130 signaling pathway, known for its potent in vitro antitumor activity. This compound induces significant ultrastructural changes in cells, leading to G0/G1 phase cell cycle arrest and promoting both apoptosis and autophagy. GP130-IN-1 is particularly valuable in research focused on triple-negative breast cancer, providing insights into the mechanisms of tumor progression and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2955243-69-1 |
| Applications | GP130 Inhibitor |
| Formula | C21H10F5NO3 |
| Molecular Weight | 419.30 |
| SMILES | O=C(N1C(C2=CC=C(O)C=C2)=CC3=C1C=CC(O)=C3)C4=C(F)C(F)=C(F)C(F)=C4F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.