Fig. 1 · Structure
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GP130 receptor agonist-1
GP130 Receptor Agonist
GP130 receptor agonist-1 is a selective agonist of the GP130 receptor, known for its ability to penetrate the blood-brain barrier and exhibit oral bioavailability. This compound demonstrates neuroprotective properties against NMDA-induced neurotoxicity, making it valuable for investigating neurodegenerative disorders and brain injury models. Its application in research may provide insights into therapeutic strategies for conditions associated with glutamatergic excitotoxicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 339303-87-6 |
| Applications | GP130 Receptor Agonist |
| Formula | C15H11FN2S |
| Molecular Weight | 270.32 |
| SMILES | FC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.