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GPLGIAGQ

Catalog No.: A30835
MMP2-Cleavable Polypeptide
GPLGIAGQ is an MMP2-cleavable polypeptide utilized as a stimulus-sensitive linker in liposomal and micellar nanocarriers for targeted tumor delivery. This compound enables the synthesis of innovative MMP2-targeted photosensitizers, enhancing the efficacy of photodynamic therapy (PDT) applications. Its selective cleavage by MMP2 facilitates precise drug release in the tumor microenvironment, making it a valuable tool in cancer research and therapy.
GPLGIAGQ 109053-09-0 MMP2-Cleavable Polypeptide
Grouped product items
Size Price Stock Qty
5mg
$80.00
In stock
10mg
$125.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGPLGIAGQ is an MMP2-cleavable polypeptide utilized as a stimulus-sensitive linker in liposomal and micellar nanocarriers for targeted tumor delivery. This compound enables the synthesis of innovative MMP2-targeted photosensitizers, enhancing the efficacy of photodynamic therapy (PDT) applications. Its selective cleavage by MMP2 facilitates precise drug release in the tumor microenvironment, making it a valuable tool in cancer research and therapy.
Product Information
Catalog NumA30835
FormulaC31H53N9O10
Molecular Weight711.81
CAS Number109053-09-0
SequenceGly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
Sequence shorteningGPLGIAGQ
SMILESC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)C)=O)[C@H](CC)C)=O)=O)CC(C)C)(=O)[C@H]1N(C(CN)=O)CCC1
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