GR 94800 is a potent and selective antagonist of the NK2 receptor, exhibiting a pKB value of 9.6, along with lower values of 6.4 and 6.0 for NK1 and NK3 receptors, respectively. This compound is valuable for investigating the role of NK2 receptors in various biological processes and can be employed in studies related to pain, inflammation, and neurogenic responses. Research applications include exploring neurokinin signaling pathways and potential therapeutic targets for related diseases.
GR 94800 is a potent and selective antagonist of the NK2 receptor, exhibiting a pKB value of 9.6, along with lower values of 6.4 and 6.0 for NK1 and NK3 receptors, respectively. This compound is valuable for investigating the role of NK2 receptors in various biological processes and can be employed in studies related to pain, inflammation, and neurogenic responses. Research applications include exploring neurokinin signaling pathways and potential therapeutic targets for related diseases.
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