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GR122222X

DNA/RNA Synthesi Inhibitor

GR122222X is a potent inhibitor of the DNA gyrase B protein, effectively disrupting DNA replication and transcription processes. This reagent is valuable for investigating the biochemical pathways involved in DNA/RNA synthesis and can be utilized in structural studies of gyrase through molecular replacement. Its unique cyclothiidine structure facilitates the crystallization of the protein fragment, enabling in-depth structural analysis and further research into antimicrobial mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	161161-54-2
Applications	DNA/RNA Synthesi Inhibitor
Formula	C₂₆H₃₅N₅O₁₁S₂
Molecular Weight	657.71
SMILES	CC1=C(O)C=C(O)C(CS)=C1C(OC([C@H](C)N(C([C@H](C)N)=O)C([C@H](C=S)NC([C@H](CO)NC([C@@H]2[C@@H](CCN2)O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.