Fig. 1 · Structure
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Granotapide
MTP Inhibitor
Granotapide is an orally active microsomal triglyceride transfer protein (MTP) inhibitor. By inhibiting MTP, Granotapide effectively reduces the absorption of cholesterol and triglycerides, making it a valuable tool for studying dyslipidemia. This compound is primarily utilized in research applications focused on lipid metabolism and associated disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 594842-13-4 |
| Applications | MTP Inhibitor |
| Formula | C39H37F3N2O8 |
| Molecular Weight | 718.71 |
| Synonyms | JTT-130 |
| SMILES | CCOC(C(C(OCC)=O)(COC(CC1=CC(C(N(C)C)=O)=C(C=C1)NC(C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)=O)=O)C4=CC=CC=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.