Grisnilimab

Catalog No.: AT0109

Grisnilimab is an IgG2a monoclonal antibody targeting CD7, implicated in tumor suppression and relevant to the pathogenesis of Wilms' tumor. This antibody functions by regulating the transcription of various target genes and may also play a role in the post-transcriptional processing of RNA. Grisnilimab is designed for research applications focusing on the molecular mechanisms of tumorigenesis and potential therapeutic interventions.

Grouped product items
Size Price Stock Qty
1mg
$320.00
In stock
5mg
$960.00
In stock
10mg
$1,520.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description

Grisnilimab is an IgG2a monoclonal antibody targeting CD7, implicated in tumor suppression and relevant to the pathogenesis of Wilms' tumor. This antibody functions by regulating the transcription of various target genes and may also play a role in the post-transcriptional processing of RNA. Grisnilimab is designed for research applications focusing on the molecular mechanisms of tumorigenesis and potential therapeutic interventions.

Product Information
Catalog NumAT0109
Molecular Weight146390
CAS Number2367001-70-3
IsotypeMouse IgG2a lambda
SpeciesMouse
SynonymsWT1
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Frequently Asked Questions
What are Biosimilar Antibodies?
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.