Fig. 1 · Structure
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GS-441524 hydrochloride
FIPV Inhibitor
GS-441524 hydrochloride is a potent inhibitor of feline infectious peritonitis virus (FIPV). This compound demonstrates significant antiviral activity, with an EC50 value of 0.78 μM in cell-based models of FIPV-infected feline cells. GS-441524 hydrochloride is utilized in research exploring coronavirus infections in both cats and humans, highlighting its relevance in studies targeting antiviral therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2378280-82-9 |
| Applications | FIPV Inhibitor |
| Formula | C12H14ClN5O4 |
| Molecular Weight | 327.72 |
| SMILES | N#C[C@@]1(C2=CC=C3N2N=CN=C3N)O[C@H](CO)[C@@H](O)[C@H]1O.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.