Signaling Pathway
Product type
Important Notice: For research use only. We do not sell to patients.
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| Discription | GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits Ca(2+) influx through recombinant TRPV4 channels and native endothelial TRPV4 currents. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
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| Catalog Num | A14201 |
|---|---|
| Formula | C37H38BrF3N4O |
| Molecular Weight | 691.62 |
| CAS Number | 1336960-13-4 |
| SMILES | C1CCN(CC1)C2CCN(CC2)CC3=C(N=C4C=C(C=CC4=C3C(=O)NC5(CC5)C6=CC=CC=C6)Br)C7=CC(=CC=C7)C(F)(F)F |
| Synonyms | GSK 2193874, GSK2193874 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 95 mg/mL (137.35 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 48 mg/mL (69.4 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.46 mL | 72.29 mL | 144.59 mL |
| 0.5 mM | 2.89 mL | 14.46 mL | 28.92 mL |
| 1 mM | 1.45 mL | 7.23 mL | 14.46 mL |
| 5 mM | 0.29 mL | 1.45 mL | 2.89 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
