GSK163929 is an orally bioavailable CCR5 antagonist, primarily targeting HIV infection. This compound demonstrates anti-HIV activity by inhibiting the CCR5 co-receptor, crucial for viral entry into host cells. GSK163929 has been evaluated for safety, showing no adverse effects in rat and dog models at specified dosages. Its properties make it a valuable tool for research in HIV therapies and co-receptor interaction studies.
GSK163929 is an orally bioavailable CCR5 antagonist, primarily targeting HIV infection. This compound demonstrates anti-HIV activity by inhibiting the CCR5 co-receptor, crucial for viral entry into host cells. GSK163929 has been evaluated for safety, showing no adverse effects in rat and dog models at specified dosages. Its properties make it a valuable tool for research in HIV therapies and co-receptor interaction studies.
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