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GSK2181236A

sGC Activator

GSK2181236A is a soluble guanylate cyclase (sGC) activator that is resistant to nitric oxide. This compound promotes vasodilation, reduces mean arterial pressure, and mitigates the progression of cardiac hypertrophy. GSK2181236A is applicable in research focused on cardiovascular diseases, including hypertension and related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	1160426-89-0
Applications	sGC Activator
Formula	C₃₁H₂₁F₆N₃O₄
Molecular Weight	613.51
SMILES	O=C(C1=C(C(F)(F)F)N(C2=NC(C3=CC=CC=C3OCC4=CC=C(C5=CC=C(OC(F)(F)F)C=C5)C=C4C)=CC=C2)N=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.