GSK2798745

Catalog No.: A20799
TRPV4 ion channel blocker
GSK2798745 is a first-in-class, highly potent, selective, orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker with IC50s of 1.8 and 1.6 nM for hTRPV4 and rTRPV4, respectively.
Grouped product items
Product Name Price Stock Qty
GSK2798745 1mg
$320.00
In stock
GSK2798745 5mg
$960.00
In stock
GSK2798745 10mg
$1,600.00
In stock
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Biological Activity
Discription GSK2798745 is a first-in-class, highly potent, selective, orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker with IC50s of 1.8 and 1.6 nM for hTRPV4 and rTRPV4, respectively.
Product Information
Catalog Num A20799
Formula C25H28N6O3
Molecular Weight 460.53
CAS Number 1419609-94-1
SMILES N#CC1=CC=C2N=CN(C[C@](CCC3)(C)C[C@@]43CN(C5=NC=C(C(C)(O)C)N=C5)C(O4)=O)C2=C1
Synonyms GSK-2798745; GSK 2798745
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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