GSK3368715 dihydrochloride

Catalog No.: A21733
PRMT inhibitor
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)).
Grouped product items
Product Name Price Stock Qty
GSK3368715 dihydrochloride 1mg
$80.00
In stock
GSK3368715 dihydrochloride 5mg
$140.00
In stock
GSK3368715 dihydrochloride 10mg
$180.00
In stock
GSK3368715 dihydrochloride 50mg
$520.00
In stock
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Biological Activity
Discription GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)).
Product Information
Catalog Num A21733
Formula C20H40Cl2N4O2
Molecular Weight 439.46
CAS Number 1628925-77-8
SMILES CNCCN(CC1=CNN=C1C2CCC(COCC)(COCC)CC2)C.Cl.Cl
Synonyms EPZ019997 dihydrochloride, EPZ-019997, EPZ 019997; GSK-3368715, GSK 3368715
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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