Fig. 1 · Structure
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GSK345931A
EP1 Antagonist
GSK345931A is an EP1 receptor antagonist that demonstrates significant central nervous system penetration in murine models. It exhibits potent analgesic effects in both acute and sub-chronic inflammatory pain models, making it a valuable tool for exploring pain mechanisms and potential therapeutic applications in pain management research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 869499-38-7 |
| Applications | EP1 Antagonist |
| Formula | C22H19ClNNaO3 |
| Molecular Weight | 403.83 |
| SMILES | O=C(C1=CC=CC(C2=C(C3=C(OCC(C)C)C=CC(Cl)=C3)C=CC=C2)=N1)O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.