Biological Activity
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.51 mL | 132.53 mL | 265.06 mL |
0.5 mM | 5.3 mL | 26.51 mL | 53.01 mL |
1 mM | 2.65 mL | 13.25 mL | 26.51 mL |
5 mM | 0.53 mL | 2.65 mL | 5.3 mL |
*The above data is based on the productmolecular weight 377.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21906 |
---|---|
CAS No. | 2079886-19-2 |
Formula | C17H21BrN4O |
M. Wt | 377.28 |
Solubility | DMSO |
Purity | >98% |
Synonyms | GSK 4028, GSK-4028 |
SMILES | BrC1=C(N[[email protected]]2C[[email protected]@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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