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GTP-γ-S

G-Protein Activator

Guanosine 5'-[γ-thio]triphosphate (GTP-γ-S) is a potent G-protein activator that enhances the stability of proteins against proteolytic degradation. It facilitates glucose transporter 4 (GLUT4) translocation through a tyrosine kinase-dependent pathway, activates phospholipases, and promotes actin polymerization. GTP-γ-S is commonly utilized in research for studying the coupling effects of G-proteins with kinase activity, as well as acting as a component in lysis buffer formulations.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	37589-80-3
Applications	G-Protein Activator
Formula	C₁₀H₁₆N₅O₁₃P₃S
Molecular Weight	539.25
Synonyms	Guanosine 5'-[γ-thio]triphosphate
SMILES	O[C@H]1[C@@H](O)[C@@H](N2C(NC(N)=NC3=O)=C3N=C2)O[C@H]1COP(O)(OP(OP(S)(O)=O)(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.