Fig. 1 · Structure
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GTPγS tetralithium
G Proteins Activator
GTPγS tetralithium is a G-protein activator known for its ability to prevent proteolytic degradation of proteins. It stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, activates phospholipases, and induces actin polymerization. This reagent is useful for coupling with G-protein α to investigate its effects on kinase activity and serves as a component in lysis buffers for various biochemical assays.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 94825-44-2 |
| Applications | G Proteins Activator |
| Formula | C10H12Li4N5O13P3S |
| Molecular Weight | 562.98 |
| Synonyms | Guanosine 5'-[γ-thio]triphosphate tetralithium |
| SMILES | O[C@H]1[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(S[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.