Fig. 1 · Structure
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Guanylin(human)
Intestinal Guanylate Cyclase Activator
Guanylin (human) is a 15-amino acid peptide that functions as an activator of intestinal guanylate cyclase. It primarily regulates electrolyte and water transport in intestinal and renal epithelia via a cyclic GMP-dependent mechanism. This endogenous peptide plays a crucial role in maintaining fluid homeostasis and is vital in studies related to gastrointestinal function and renal physiology. Research applications include investigating gastrointestinal disorders and kidney function modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 183200-12-6 |
| Applications | Intestinal Guanylate Cyclase Activator |
| Formula | C58H87N15O21S4 |
| Molecular Weight | 1458.66 |
| SMILES | C([C@@H]1NC(=O)[C@H](C)NC(=O)[C@]2(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC([C@@H](NC(CNC(=O)[C@@H]3CCCN3)=O)[C@@H](C)O)=O)CSSC[C@](NC(=O)[C@H](C)NC(=O)[C@H](C)NC1=O)(C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC(=O)N[C@H](C(O)=O)CSSC2)[H])[H])[H])[H])C4=CC=C(O)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.