Fig. 1 · Structure
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GW-3333
TACE/MMP Inhibitor
GW-3333 is a potent inhibitor of TNF-alpha-converting enzyme (TACE) and matrix metalloproteinases (MMPs). By inhibiting TACE, GW-3333 effectively reduces the production of tumor necrosis factor-alpha (TNF-alpha), which plays a critical role in inflammatory processes. This compound is primarily utilized in research applications related to arthritis and other inflammatory diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 212609-68-2 |
| Applications | TACE/MMP Inhibitor |
| Formula | C22H36N4O4 |
| Molecular Weight | 420.55 |
| SMILES | CC[C@@H]([C@H](NC([C@@H]([C@@H](N(O)C=O)C(C)C)CC(C)C)=O)C(NC1=CC=CC=N1)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.