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GW791343 HCl

P2X7 modulator

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Catalog No. A11107

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GW791343 HCl 5mg A11107-5
GW791343 HCl 10mg A11107-10
GW791343 HCl 25mg A11107-25
GW791343 HCl 50mg A11107-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GW791343 HCl acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.

GW791343 HCl

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Chemical Information

Catalog Num A11107
Actions Modulator
M. Wt 483.8
Formula C20H24F2N4O.3HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1019779-04-4
Synonyms GW-791343

Biological Activity

GW791343 HCl acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.67 mL 103.35 mL 206.7mL
0.5 mM 4.13 mL 20.67 mL 41.34 mL
1 mM 2.07 mL 10.33 mL 20.67 mL
5 mM 0.41 mL 2.07 mL 4.13 mL

*The above data is based on the productmolecular weight 483.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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