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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11107 |
|---|---|
| Actions | Modulator |
| M. Wt | 483.8 |
| Formula | C20H24F2N4O.3HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1019779-04-4 |
| Synonyms | GW-791343 |
| SMILES code | CC1=C(C=C(C=C1)CN2CCNCC2)NC(=O)CNC3=CC(=C(C=C3)F)F.Cl.Cl.Cl |
| Chemical Name | 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide trihydrochloride |
Description |
GW791343 HCl acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.67 mL | 103.35 mL | 206.7mL |
| 0.5 mM | 4.13 mL | 20.67 mL | 41.34 mL |
| 1 mM | 2.07 mL | 10.33 mL | 20.67 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.13 mL |
*The above data is based on the productmolecular weight 483.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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