Gymnoascolide A

Catalog No.: A27162
Fungal Metabolite
Gymnoascolide A is a fungal metabolite derived from M. filamentosa, recognized for its vasodilatory properties. At a concentration of 1 µM, it effectively inhibits calcium-induced contractions in isolated rat aortic rings, highlighting its potential role in vascular research. This compound may be valuable for studying mechanisms of vasodilation and the modulation of vascular tone.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGymnoascolide A is a fungal metabolite derived from M. filamentosa, recognized for its vasodilatory properties. At a concentration of 1 µM, it effectively inhibits calcium-induced contractions in isolated rat aortic rings, highlighting its potential role in vascular research. This compound may be valuable for studying mechanisms of vasodilation and the modulation of vascular tone.
Product Information
Catalog NumA27162
FormulaC17H14O2
Molecular Weight250.29
CAS Number865092-05-3
SMILESO=C1OCC(CC2=CC=CC=C2)=C1C3=CC=CC=C3
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