Fig. 1 · Structure
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H-D-Phe-Pip-Arg-pNA dihydrochloride
Chromogenic Substrate
H-D-Phe-Pip-Arg-pNA dihydrochloride is a chromogenic substrate specifically designed for thrombin activity assessment. It is based on the N-terminal sequence of the A alpha chain of fibrinogen, the natural substrate for thrombin. This reagent facilitates the measurement of antithrombin-heparin cofactor (AT-III) levels, providing a sensitive, accurate, and straightforward method for applications in coagulation research and diagnostics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 62354-65-8 |
| Applications | Chromogenic Substrate |
| Formula | C27H38Cl2N8O5 |
| Molecular Weight | 625.55 |
| Synonyms | S-2238 dihydrochloride |
| SMILES | N=C(N)NCCC[C@@H](C(NC(C1NCCCC1)=O)=O)N(C([C@@H](CC2=CC=CC=C2)N)=O)C3=CC=C([N+]([O-])=O)C=C3.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.