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H-D-Phe-Pip-Arg-pNA

Chromogenic Substrate

H-D-Phe-Pip-Arg-pNA is a chromogenic substrate specifically designed for thrombin activity. By mimicking the N-terminal sequence of the A alpha chain of fibrinogen, it effectively facilitates the assessment of thrombin's enzymatic function. This reagent is commonly employed in assays to measure the activity of antithrombin-heparin cofactor (AT-III), providing a sensitive and precise method for evaluating anticoagulant therapies and thrombotic disorders.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	64815-81-2
Applications	Chromogenic Substrate
Formula	C₂₇H₃₆N₈O₅
Molecular Weight	552.63
Synonyms	S-2238
SMILES	N[C@H](Cc1ccccc1)C(=O)N1CCCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.