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H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA

Pin1 Chromogenic Substrate

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate specifically designed for the prolyl isomerase Pin1. This reagent facilitates the study of Pin1 activity by enabling the detection of phosphoserine-proline bonds in mitotic phosphoproteins, critical for understanding cell cycle regulation. The compound is invaluable in biochemical assays and research focused on mitosis and related signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	202739-41-1
Applications	Pin1 Chromogenic Substrate
Formula	C₄₉H₅₉N₁₂O₁₃P
Molecular Weight	1055.04
SMILES	C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(NC4=CC=C(N(=O)=O)C=C4)=O)CCCNC(=N)N)=O)CCC3)COP(=O)(O)O)=O)=O)=O)N)C=5C=6C(NC5)=CC=CC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.