HAA-09 is a potent anti-influenza agent that targets the PB2_cap binding domain of the influenza polymerase complex. It exhibits strong inhibitory activity against influenza A virus, with an EC50 of 0.03 μM, and demonstrates polymerase inhibition with an IC50 of 0.06 ± 0.004 μM. HAA-09 effectively blocks viral replication while exhibiting minimal cytotoxicity, making it a valuable compound for research into antiviral therapies and mechanisms of influenza virus control.
HAA-09 is a potent anti-influenza agent that targets the PB2_cap binding domain of the influenza polymerase complex. It exhibits strong inhibitory activity against influenza A virus, with an EC50 of 0.03 μM, and demonstrates polymerase inhibition with an IC50 of 0.06 ± 0.004 μM. HAA-09 effectively blocks viral replication while exhibiting minimal cytotoxicity, making it a valuable compound for research into antiviral therapies and mechanisms of influenza virus control.
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