Fig. 1 · Structure

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HAA-09

Anti-influenza Virus Agent

HAA-09 is a potent anti-influenza agent that targets the PB2_cap binding domain of the influenza polymerase complex. It exhibits strong inhibitory activity against influenza A virus, with an EC50 of 0.03 μM, and demonstrates polymerase inhibition with an IC50 of 0.06 ± 0.004 μM. HAA-09 effectively blocks viral replication while exhibiting minimal cytotoxicity, making it a valuable compound for research into antiviral therapies and mechanisms of influenza virus control.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1422051-33-9
Applications Anti-influenza Virus Agent
Formula C17H18F2N6O2
Molecular Weight 376.36
SMILES
CC(C)(N(NC1=C(C=NC(C2=CNC3=C2C=C(C=N3)F)=N1)F)CC(O)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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