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hAChE-IN-4

Cholinesterase (ChE) Inhibitor

hAChE-IN-4 is a potent inhibitor of human acetylcholinesterase (hAChE) with an IC50 value of 0.25 μM, demonstrating effective permeability across the blood-brain barrier. This compound plays a significant role in research related to Alzheimer's disease, where modulation of cholinergic activity is critical. Its use can aid in exploring therapeutic strategies targeting cholinesterase activity in neurodegenerative disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2983723-58-4
Applications	Cholinesterase (ChE) Inhibitor
Formula	C₃₀H₂₃Cl₃N₂O₃
Molecular Weight	565.87
SMILES	O=C(C1=CC=C(Cl)C=C1)COC2=CC3=C(C=C2)C(C4=CC=C(Cl)C(Cl)=C4)C5=C(N)C6=C(N=C5O3)CCCC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.