Harman-d3 is a deuterium-labeled derivative of Harmane, a compound known for its role as a benzodiazepine receptor antagonist, exhibiting an IC50 of 7 μM. It demonstrates additional inhibitory activity on several receptors, including mACh and opioid receptors, with IC50 values of 24 μM and 2.8 μM, respectively. Harman-d3 is useful in research focused on neuropharmacology due to its potential antidepressant, anti-anxiety, and analgesic effects. Furthermore, it has been shown to influence dopamine biosynthesis and enhance mutagenic effects in cellular assays, making it a valuable tool for studying various biological processes.
Harman-d3 is a deuterium-labeled derivative of Harmane, a compound known for its role as a benzodiazepine receptor antagonist, exhibiting an IC50 of 7 μM. It demonstrates additional inhibitory activity on several receptors, including mACh and opioid receptors, with IC50 values of 24 μM and 2.8 μM, respectively. Harman-d3 is useful in research focused on neuropharmacology due to its potential antidepressant, anti-anxiety, and analgesic effects. Furthermore, it has been shown to influence dopamine biosynthesis and enhance mutagenic effects in cellular assays, making it a valuable tool for studying various biological processes.
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