Fig. 1 · Structure
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HBV-IN-14
cccDNA Inhibitor
HBV-IN-14 is a potent inhibitor of covalently closed circular DNA (cccDNA), a critical component in the life cycle of hepatitis B virus (HBV) as it acts as the template for viral RNA transcription and subsequent viral DNA synthesis. This pyridinopyrimidinones compound demonstrates significant antiviral properties, making it a valuable tool for research focused on HBV infection mechanisms and potential therapeutic interventions. The compound is poised for applications in studies aimed at elucidating HBV-related pathogenesis and identifying novel treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2712529-19-4 |
| Applications | cccDNA Inhibitor |
| Formula | C22H21ClN2O5 |
| Molecular Weight | 428.87 |
| SMILES | O=C1C=C(C2=CC=C(C=C2)OCCO[C@H]3C[C@](C)(C3)C(O)=O)N=C4N1C=CC=C4Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.