Fig. 1 · Structure

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HCTZ-CH2-HCTZ

Cat. No. A84914 CAS 402824-96-8

HCTZ Isomer

HCTZ-CH2-HCTZ is an isomer of hydrochlorothiazide (HCTZ), a thiazide-class diuretic that functions primarily by inhibiting the transforming growth factor-beta (TGF-β)/Smad signaling pathway. This compound exhibits biological activity pertinent to fluid regulation and vascular integrity, making it valuable in research applications focused on cardiovascular biology and renal function. Its unique structure may provide insights into the mechanism of action and therapeutic potential of diuretics in various pathological conditions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 402824-96-8
Applications HCTZ Isomer
Formula C15H16Cl2N6O8S4
Molecular Weight 607.49
SMILES
O=S(N)(C1=C(Cl)C=C(N(CNS2(=O)=O)CNS(=O)(C3=C(Cl)C=C(NCNS4(=O)=O)C4=C3)=O)C2=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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