Fig. 1 · Structure
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Heliquinomycin
DNA Helicase Inhibitor
Heliquinomycin is a potent inhibitor of DNA helicase, exhibiting a Ki value of 6.8 μM. This compound disrupts DNA and RNA synthesis, making it a valuable tool in studies of nucleic acid metabolism. Additionally, Heliquinomycin demonstrates activity against Gram-positive bacterial strains and shows potential in inhibiting cancer cell proliferation, highlighting its relevance in microbiological and cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 178182-49-5 |
| Applications | DNA Helicase Inhibitor |
| Formula | C33H30O17 |
| Molecular Weight | 698.58 |
| SMILES | OC1=C([C@H]([C@]2(OC3=C(O)C(C(OC(C(OC)=O)=C4)=O)=C4C=C3C[C@H]2O)O5)O[C@H]6C[C@H]([C@H]([C@@H](O6)C)O)OC)C5=C(O)C(C(C(OC)=C7)=O)=C1C7=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.