Fig. 1 · Structure
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hGGPPS-IN-1
hGGPPS Inhibitor
hGGPPS-IN-1 is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS), targeting a critical enzyme involved in the isoprenoid biosynthetic pathway. This compound demonstrated effective induction of apoptosis in multiple myeloma (MM) cells, showcasing its potential as an antimyeloma agent in vivo. hGGPPS-IN-1 represents a promising tool for researchers investigating therapeutic strategies against multiple myeloma and related malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1429012-38-3 |
| Applications | hGGPPS Inhibitor |
| Formula | C13H13N3O6P2S |
| Molecular Weight | 401.27 |
| SMILES | O=P(O)(C(P(O)(O)=O)NC1=C2C=CSC2=NC(C3=CC=CC=C3)=N1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.