Fig. 1 · Structure
Documents & Downloads
hGGPPS-IN-2
hGGPPS Inhibitor
hGGPPS-IN-2 is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS) and functions through selective disruption of geranylgeranylation processes. This compound induces targeted apoptosis in multiple myeloma (MM) cells, demonstrating significant antimyeloma activity both in vitro and in vivo. hGGPPS-IN-2 serves as a valuable tool for research into the molecular mechanisms underlying myeloma pathogenesis and potential therapeutic strategies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2241547-82-8 |
| Applications | hGGPPS Inhibitor |
| Formula | C20H18FN5O7P2S |
| Molecular Weight | 553.40 |
| SMILES | O=C(NC1=CC=CC(C2=NC(NC(P(O)(O)=O)P(O)(O)=O)=C3C=CSC3=N2)=C1)NC4=CC=C(C=C4)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.