His-Cys-Lys-Phe-Trp-Trp

Catalog No.: A75639
HIV Integrase Inhibitor
His-Cys-Lys-Phe-Trp-Trp is an HIV integrase inhibitor, exhibiting an IC50 of 2 μM. This compound impedes the integrase enzyme's function, thereby preventing viral DNA integration into the host genome. His-Cys-Lys-Phe-Trp-Trp is valuable for research focused on HIV pathogenesis and the development of antiretroviral therapies.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHis-Cys-Lys-Phe-Trp-Trp is an HIV integrase inhibitor, exhibiting an IC50 of 2 μM. This compound impedes the integrase enzyme's function, thereby preventing viral DNA integration into the host genome. His-Cys-Lys-Phe-Trp-Trp is valuable for research focused on HIV pathogenesis and the development of antiretroviral therapies.
Product Information
Catalog NumA75639
FormulaC46H55N11O7S
Molecular Weight906.06
CAS Number172546-75-7
SequenceHis-Cys-Lys-Phe-Trp-Trp
Sequence shorteningHCKFWW
SMILESC([C@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)CS)=O)CCCCN)=O)=O)C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(O)=O)=O)C=5C=6C(NC5)=CC=CC6
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