Fig. 1 · Structure
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Histatin 5
Antimicrobial Agent
Histatin 5 is an antimicrobial peptide that targets host matrix metalloproteinases MMP-2 and MMP-9, exhibiting inhibitory concentrations with IC50 values of 0.57 μM and 0.25 μM, respectively. Its primary biological activity includes the modulation of matrix remodeling and inflammatory processes. Histatin 5 is beneficial for research applications focused on antimicrobial mechanisms and the study of extracellular matrix dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 115966-68-2 |
| Applications | Antimicrobial Agent |
| Formula | C133H195N51O33 |
| Molecular Weight | 3036.29 |
| SMILES | [C@@H](CC1=CN=CN1)(NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@H](CC4=CN=CN4)NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC6=CN=CN6)NC([C@@H](NC([C@H](CC(O)=O)N)=O)CO)=O)=O)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=O)=O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CN=CN7)C(N[C@@H](CC8=CN=CN8)C(N[C@H](C(N[C@@H](CC9=CN=CN9)C(N[C@H](C(NCC(N[C@@H](CC%10=CC=C(O)C=C%10)C(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CO)=O)=O)=O)CCCCN)=O)CCC(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.