HIV-1 protease-IN-10 is a potent HIV-1 latency reversing agent with an IC50 of 0.22 μM. This compound selectively binds to the PKCδ C1b domain, exhibiting an IC50 of 0.69 μM. Additionally, HIV-1 protease-IN-10 demonstrates stability against esterase-mediated hydrolysis, making it suitable for research applications in HIV latency and reactivation studies.
HIV-1 protease-IN-10 is a potent HIV-1 latency reversing agent with an IC50 of 0.22 μM. This compound selectively binds to the PKCδ C1b domain, exhibiting an IC50 of 0.69 μM. Additionally, HIV-1 protease-IN-10 demonstrates stability against esterase-mediated hydrolysis, making it suitable for research applications in HIV latency and reactivation studies.
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