HIV-1 protease-IN-5

Catalog No.: A51865
HIV-1 Protease Inhibitor
HIV-1 protease-IN-5 is a potent inhibitor of HIV-1 protease, exhibiting an IC50 of 1.64 nM. This compound demonstrates significant efficacy against both wild-type and darunavir-resistant variants of HIV-1, making it a valuable tool for antiviral research. Its mechanism of action is crucial for developing therapeutic strategies to combat HIV-1 infections and resistance.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHIV-1 protease-IN-5 is a potent inhibitor of HIV-1 protease, exhibiting an IC50 of 1.64 nM. This compound demonstrates significant efficacy against both wild-type and darunavir-resistant variants of HIV-1, making it a valuable tool for antiviral research. Its mechanism of action is crucial for developing therapeutic strategies to combat HIV-1 infections and resistance.
Product Information
Catalog NumA51865
FormulaC27H29F3N2O7S
Molecular Weight582.59
CAS Number2525173-96-8
SMILESC[C@H](CN(S(=O)(C1=CC=C(C=C1)C(F)(F)F)=O)C[C@H]([C@@H](NC(C2=CC(O)=C(C=C2)O)=O)CC3=CC=CC=C3)O)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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