HIV-1 protease-IN-6 is a potent inhibitor of HIV-1 protease, demonstrating an impressive IC50 of 21 pM and a Ki of 4.7 pM. This compound displays significant antiviral activity against darunavir-resistant variants, surpassing that of the wild type virus. Its high potency and efficacy make it a valuable tool for researching HIV-1 replication and resistance mechanisms.
HIV-1 protease-IN-6 is a potent inhibitor of HIV-1 protease, demonstrating an impressive IC50 of 21 pM and a Ki of 4.7 pM. This compound displays significant antiviral activity against darunavir-resistant variants, surpassing that of the wild type virus. Its high potency and efficacy make it a valuable tool for researching HIV-1 replication and resistance mechanisms.
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