HIV-1 protease-IN-8 is a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.32 nM. This compound effectively inhibits wild-type HIV-1 (HIV-1NL4-3) with an IC50 of 0.29 μM and a drug-resistant variant (HIV-1MDR) with an IC50 of 1.90 μM. Its strong antiviral activity against both strains makes HIV-1 protease-IN-8 a valuable tool for research in HIV treatment and drug resistance studies.
HIV-1 protease-IN-8 is a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.32 nM. This compound effectively inhibits wild-type HIV-1 (HIV-1NL4-3) with an IC50 of 0.29 μM and a drug-resistant variant (HIV-1MDR) with an IC50 of 1.90 μM. Its strong antiviral activity against both strains makes HIV-1 protease-IN-8 a valuable tool for research in HIV treatment and drug resistance studies.
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