HJ03 is a potent inducer of ferroptosis that targets DNA damage pathways. It enhances intracellular reactive oxygen species (ROS) levels, facilitates Fe2+ accumulation, and promotes lipid peroxidation, ultimately leading to the induction of DNA adducts and interstrand crosslinks. By inhibiting DNA replication and transcription, HJ03 effectively arrests the cell cycle at the G2/M phase and triggers apoptosis. This reagent is valuable for investigating glioblastoma multiforme and colorectal cancer research.
HJ03 is a potent inducer of ferroptosis that targets DNA damage pathways. It enhances intracellular reactive oxygen species (ROS) levels, facilitates Fe2+ accumulation, and promotes lipid peroxidation, ultimately leading to the induction of DNA adducts and interstrand crosslinks. By inhibiting DNA replication and transcription, HJ03 effectively arrests the cell cycle at the G2/M phase and triggers apoptosis. This reagent is valuable for investigating glioblastoma multiforme and colorectal cancer research.
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